Divya Lenkala

Company: BioNTech

Job title: Former Group Leader, T-Cell Immunology

Seminars:

Advancing Potency Assays for TIL Therapies to Prevent Clinical Holds & Streamline Route to Patients 11:30 am

Comparing the development of potency assays for CAR-Ts, TCR-Ts, ex vivo T-cell therapies and TILs, highlighting the unique challenges faced by personalized T-cell therapies like TILs Exploring the complexities of developing potency assays for TIL therapies, including surrogate assays and GMP-ready validation Discussing the difficulties in validating potency assays that accurately target the mechanism of…Read more

day: Conference Day Two CMC Track AM

Integrating AI in the Manufacturing & Analytical Development of TIL Therapies 9:30 am

Exploring how AI can streamline potency assay development and improve analysis of complex manufacturing data Addressing challenges in understanding TIL mechanisms of action and their impact on CMC assay design and validation Designing data-driven potency assays that reflect clinical benefit, using matrix-based approaches and AI-enhanced modellingRead more

day: Workshop Day CMC Track AM