Targeting Clonal Neoantigens with Precision T-Cell Therapies: Key Mechanistic Insights From cNeT Clinical Trials

Time: 11:00 am
day: Conference Day One - Track B - AM

Details:

Unique translational science platform enables us to track the active component of TIL (clonal neoantigen reactive T-cell) in patients and determine key mechanisms underpinning in vivo activity 

Key insights to date include: 

  • Impact of host conditioning in T-cell persistence and engraftment 
  • Critical role of evasion mechanisms (such as HLA loss) in resistance to T-cell based therapies

Speakers: