Counteracting T-Cell Exhaustion: T-Cell Therapy Meets Organelle Medicine
Time: 12:00 pm
day: Conference Day Two - Track A - AM
Details:
- Bone marrow stromal cells transfer mitochondria to CD8+ T cells via intercellular nanotube connections.
- Mitochondrial transfer augments CD8+ T cell metabolic fitness
- Mitochondrial transfer empowers TCR and CAR-modified T cells as well as TILs to counteract exhaustion and fight tumors more effectively.
