Utilizing Multiplex CRISPR Gene Editing to Assess New Classes of Intra Cellular Immune Checkpoint Molecules for Application in TIL
Time: 12:00 pm
day: Day Two
Details:
• Comparing the function of CISH deletion relative to both extracellular and intracellular immune checkpoints in neoantigen cytolysis models
• Demonstrating intra-cellular immune checkpoint protein CISH can potentially enhance anti-tumor responses against a broad range of cancer types regardless of PD-L1 biomarker status
• Considering next generation checkpoints and the application to TIL
