Using CD39/CD103 to Isolate Tumor-Reactive CD8 TIL: Bench to Bedside

Time: 11:30 am
day: Day Two

Details:

  • CD39/CD103 double positive CD8 TIL are highly enriched for tumor reactivity
  • These cells can be expanded from thousands to billions even though they have a somewhat exhausted phenotype in tumors
  • These cells have been found in all solid tumors investigated so far, but their frequency is variable depending on the tumor type

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